In Opera GX 119.0.5497.78, if you goto the URL opera://settings/early_bird and enable "Revived GX Profiles", the profile page at the URL opera://settings/profiles will be a different design. The cool thing about that is you can click on the profile there to open the profile.
Further, if you click the menu at the top left of Opera and scroll down, you'll now see a "Profile" submenu where you can click a specific profile to launch it.
All that is supposed to work for macOS too I guess.
The updates in my previous comment still apply with this Early Bird option.